Buccal Swab
Who can benefit from SNP testing?
Researchers have identified thousands of SNPs that relate to almost every chronic disease. Truth is, everybody has SNPs. SNPs are common and generally do not result in life-threatening presentations like genetic mutations, which are rare. SNPs are more subtle and act by reducing cellular functions and ultimately an optimal quality of life. Genomic testing can minimize risk by identifying hidden gene polymorphisms that may promote chronic disease. Many people mistakenly assume that the presence of a SNP means they are destined to experience the associated disease. Fortunately, most genes have flexible expressions and often are influenced by modifiable environmental, diet, and lifestyle factors.
In some instances, genotypic SNP testing may prompt phenotypic monitoring of associated biomarkers. For example, if a patient has a polymorphism for MTHFR, homocysteine may be more closely monitored.
SNP testing may be appropriate for patients with:
Chronic conditions that resist treatment
Family history of cardiovascular disease, mood disorders, Alzheimer's, cancer, or autoimmune disease
Inflammatory conditions
Cardiovascular disease
Mood disorders
Osteoporosis
Metabolic disorders (insulin resistance)
Chemical sensitivity
Asthma and lung problems
Cognitive decline
The genomic SNP tests (APOE, MTHFR, TNFA, and COMT) detect genetic variations.
ApoE - Apolipoprotein E is involved in lipid metabolism and certain polymorphisms can result in increased cardiovascular disease risk and Alzheimer's disease.
MTHFR (C677T, A1298C) - Methyl tetrahydrofolate Reductase - Polymorphisms of this enzyme can disrupt the metabolism of homocysteine, resulting in its accumulation as well as impaired methylation. The presence of these SNPs can increase risk of cardiovascular disease, blood vessel damage, thrombosis (blood clots), stroke, and degenerative aging.
COMT - Catechol-O-Methyltransferase polymorphisms can result in reduced enzyme activity associated with neuropsychiatric disorders, impaired estrogen metabolism, and increased sensitivity to pain.
TNFα - Tumor Necrosis Factor-alpha is a proinflammatory cytokine and polymorphisms are associated with inflammation, oxidative stress, and numerous disease implications.
Buccal Swab
Who can benefit from SNP testing?
Researchers have identified thousands of SNPs that relate to almost every chronic disease. Truth is, everybody has SNPs. SNPs are common and generally do not result in life-threatening presentations like genetic mutations, which are rare. SNPs are more subtle and act by reducing cellular functions and ultimately an optimal quality of life. Genomic testing can minimize risk by identifying hidden gene polymorphisms that may promote chronic disease. Many people mistakenly assume that the presence of a SNP means they are destined to experience the associated disease. Fortunately, most genes have flexible expressions and often are influenced by modifiable environmental, diet, and lifestyle factors.
In some instances, genotypic SNP testing may prompt phenotypic monitoring of associated biomarkers. For example, if a patient has a polymorphism for MTHFR, homocysteine may be more closely monitored.
SNP testing may be appropriate for patients with:
Chronic conditions that resist treatment
Family history of cardiovascular disease, mood disorders, Alzheimer's, cancer, or autoimmune disease
Inflammatory conditions
Cardiovascular disease
Mood disorders
Osteoporosis
Metabolic disorders (insulin resistance)
Chemical sensitivity
Asthma and lung problems
Cognitive decline
The genomic SNP tests (APOE, MTHFR, TNFA, and COMT) detect genetic variations.
ApoE - Apolipoprotein E is involved in lipid metabolism and certain polymorphisms can result in increased cardiovascular disease risk and Alzheimer's disease.
MTHFR (C677T, A1298C) - Methyl tetrahydrofolate Reductase - Polymorphisms of this enzyme can disrupt the metabolism of homocysteine, resulting in its accumulation as well as impaired methylation. The presence of these SNPs can increase risk of cardiovascular disease, blood vessel damage, thrombosis (blood clots), stroke, and degenerative aging.
COMT - Catechol-O-Methyltransferase polymorphisms can result in reduced enzyme activity associated with neuropsychiatric disorders, impaired estrogen metabolism, and increased sensitivity to pain.
TNFα - Tumor Necrosis Factor-alpha is a proinflammatory cytokine and polymorphisms are associated with inflammation, oxidative stress, and numerous disease implications.
Genomic Add-On is only available with the purchase of Metabolomix +.
